Sickle cell anemia research articles

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August undefined, 2024

WebMar 21, 2024 · Abstract. BACKGROUND: Sickle cell disease (SCD) is an autosomal recessive hereditary condition characterized by chronic hemolytic anemia and painful vaso-occlusive episodes. Homozygous sickle cell patients are at increased risk of morbidity and mortality from malaria. Autoimmune hemolytic anemia (AIHA) secondary to, or in the setting of, … WebJun 16, 2024 · Activating a protein in red blood cells may improve anemia and alleviate acute episodes of severe pain for people living with sickle cell disease. Swee Lay Thein, …

Sickle Cell Disease in Children - Lucile Packard …

WebResearch output: Contribution to journal › Article › Academic › peer-review. TY - JOUR. T1 - Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curacao: Two Case Reports. AU - Moesker, Fleur. AU - Muskiet, FD. AU - Koeijers, JJ. AU - Fraaij, Pieter. AU - … WebSickle Cell Anemia (SCA) is the most common genetic disease worldwide caused by a single mutation in the gene HBB. ... Research Article. Clinical and biological profile of … flights to ocean city

Sickle Cell Disease: A Review - PubMed

WebMar 8, 2024 · Background: Sickle cell anemia is the hereditary disorder which is the number of red blood cell or amount of hemoglobin is low. Red blood cell contains hemoglobin protein that it enables them to carry oxygen from the lungs and deliver it to all parts of the body. Chronic organ damage sickle cell anemia is the most common form of sickle cell … WebIntroduction Sickle cell disease (SCD) disproportionately impacts Adivasi (tribal) communities in India. Current research has focused on epidemiological and biomedical … WebMar 29, 2024 · Transfusion therapy for sickle cell anemia is limited by the development of antibodies to foreign red cells. To evaluate the frequency and risk factors associated with such alloimmunization, we determined the transfusion history, red-cell phenotype, and development of alloantibodies in 107 black patients with sickle cell anemia who received … cheryl rowell

Frontiers Sickle Cell Anemia: Variants in the CYP2D6, CAT, and ...

Serum homocysteine and disease severity in sickle cell anemia …

WebMay 1, 2014 · The Stroke Prevention Trial in Sickle Cell Anemia (STOP) trial demonstrated that elevated transcranial doppler velocity can identify SCD children with a high risk of stroke and that exchange transfusion reduces that risk. 9, 10 Unfortunately, studies fail to show similar protection in adults. 2 Increased transcranial doppler velocity identifies ... WebArticle Subjects: WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 170 Hemolytic anemia (e.g., Sickle cell anemia) WS Pediatrics > WS 20 Research (General) Faculty: Department: cherylrowelawyer outlook.comWebApr 13, 2024 · Various innovative medications that were created in the late 1990s and utilized to treat sickle cell disease are examined in this study and the most important developments of the decade are focused on. Sickle cell disease is a fatal systemic condition characterized by acute painful episodes, persistent anemia, ongoing organ damage, organ … flights to oconomowoc wi

"WebOct 23, 2024 · Sickle cell anemia. Sickle cell anemia is the most common and severe type of SCD. It develops when a person inherits two hemoglobin S genes — one from each … " - Sickle cell anemia research articles

Sickle cell anemia research articles

The Foundation for Sickle Cell Disease Research

WebCyberLeninka. Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review – topic of research paper in Clinical medicine. Download scholarly article PDF and read for free on CyberLeninka open science hub. WebAug 24, 2024 · Moyamoya disease (MMD) is an unusual vasculopathy in which the blood vessels of the brain are occluded, resulting in thrombosis. When MMD occurs in association with an underlying pathology, it is known as moyamoya syndrome. The association of moyamoya syndrome with sickle cell disease is uncommon. Herein, we report a case of …

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WebMar 9, 2024 · Sickle cells can block blood flow to an area of the brain. Signs of stroke include seizures, weakness or numbness of the arms and legs, sudden speech difficulties, and loss of consciousness. If your child has … WebMay 17, 2024 · Metrics. Over 110 yr ago, the first description of a West Indian student with sickle cell disease (SCD) was reported by Dr Herrick in Chicago, USA, opening the way to …

WebJul 29, 2024 · The objective of the present article is to highlight the need for attention to Quality of Life of patients with Sickle Cell Disease living in Italy. The transformation of sickle cell disease from a severe life-threatening disease of childhood into a chronic, lifelong condition due to the significant improvements in care and treatment options, imposes … WebIn the 100 years since sickle cell anemia (SCA) was first described in the medical literature, studies of its molecular and pathophysiological basis have been at the vanguard of …

WebJan 21, 2024 · Therapeutic landscape for sickle cell disease. Hydroxyurea was a breakthrough in reducing the frequency of pain crises. But the early initiation of the drug likely also delays and, in some cases, prevents organ damage. It inhibits blood sickling by increasing fetal hemoglobin in red blood cells and reduces white blood cells to limit …

WebSickle cell disease (SCD) is a collection of inherited blood disorders that affect a substantial number of people in the U.S., particularly African Americans. People with SCD have an …

WebOct 10, 2024 · Sickle cell disease (SCD) affects about 100 000 persons in the United States (). 1 The disease causes red blood cells to lose their normal disc shape and become sickle shaped and rigid.These sickle-shaped cells adhere to vascular walls, impede blood flow and oxygenation, and cause episodes of intense pain and other complications that affect … flights to obzorWebMar 4, 2024 · Sickle cell disease, which also refers to sickle cell anemia, is a blood disorder inherited genetically. ... Racism permeates all parts of our society, including the research, ... flights to ocho riosWebMar 28, 2024 · Solovey A, Lin Y, Browne P, Choong S, Wayner E, Hebbel RP. Circulating activated endothelial cells in sickle cell anemia. N Engl J Med. 1997 Nov 27;337(22):1584-90. doi: 10.1056/NEJM199711273372203. cheryl rowe obituaryWebResearchGate. PDF) Sickle Cell Anemia, the First Molecular Disease: Overview of Molecular Etiology, Pathophysiology, and Therapeutic Approaches flights to odessa moWebDec 13, 2024 · Sickle cell disease is caused by mutations in the beta-globin gene, leading to the production of abnormal hemoglobin, the oxygen-carrying molecule in red blood cells. Normal red blood cells are shaped like donuts, but in sickle cell disease, the abnormal hemoglobin causes red blood cells to stiffen and adopt a spiky, sickle-like shape. cheryl rowe-rendlemanWebA study of media effectiveness for sickle cell anemia education in a rural community. J Natl Med Assoc. 1979 Nov; 71 (11):1055–1057. [PMC free article] [Google Scholar] Calderón JL, Baker RS, Wolf KE. Focus groups: a qualitative method complementing quantitative research for studying culturally diverse groups. flights to odenseWebMar 24, 2024 · Others offer benefits. Some can do both. And the mutation that underlies sickle cell disease is one that can be both good and very bad. Sickle cell disease is caused by a molecular change in the body’s hemoglobin. Hemoglobin is the molecule in red blood cells that transports oxygen to tissues throughout the body. flights to oceanside ca