Klotho alpha
WebKlotho levels are associated with insulin production in human and animal studies. The Centers for Disease Control indicate that >29 million Americans are living with diabetes, … Webα-Klotho is a key player that integrates a multi-step regulatory system of calcium metabolism and phosphate homeostasis. α-klotho was identified as an extremely down-regulated gene in the genetic mutation mouse (Klotho mouse) of which phenotype is very similar to various symptoms of human aging. See Description below for more $827.00 …
Klotho alpha
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WebNational Center for Biotechnology Information WebKlotho, also called Klotho-alpha, is the founding member of the Klotho family within the glycosidase-1 superfamily (1, 2). Klotho is expressed in areas concerned with calcium regulation, predominantly in the kidney distal convoluted tubules, but also in the brain choroid plexus (which produces cerebrospinal fluid) and the parathyroid (1).
Webalpha-Klotho: a regulator that integrates calcium homeostasis. Intensive study on calcium homeostasis regulation over the past several decades has established a systematized … WebKlotho, also called Klotho-alpha, is the founding member of the Klotho family within the glycosidase-1 superfamily (1, 2). Klotho is expressed in areas concerned with calcium …
WebJun 1, 2003 · Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. ... 8.A.49.1.2 the klotho auxiliary protein (klotho) family; Names & Taxonomy. Protein names. Recommended name. Beta-klotho. Short names. BKL; BetaKlotho. … WebAug 15, 2015 · The anti-aging gene klotho plays an important role in Ca(2+) and phosphate homeostasis. Membrane-bound klotho is an essential coreceptor for fibroblast growth factor-23 and can be cleaved by proteases, including a disintegrin and metalloproteinase (ADAM)10 and ADAM17.
WebKlotho is an anti-aging protein with pleiotropic actions that exerts organ protection. Several lines of evidence support the notion that Klotho functions as a human aging-suppression molecule. Polymorphisms of …
WebJan 21, 2024 · Klotho encodes alpha-Klotho (αKl) that possesses a single-pass transmembrane domain and is expressed in the distal tubule of kidneys, parathyroid … the goldwater rule in psychologyWebKlotho protein is a β-glucuronidase capable of hydrolyzing steroid β-glucuronides. Two molecules are produced by the Klotho gene, a membrane bound form and a circulating … the goldwater rule meaningWebMar 28, 2024 · Klotho Ameliorates Vascular Calcification via Promoting Autophagy. Life extension factor klotho regulates behavioral responses to stress via modulation of GluN2B function in the nucleus accumbens. NRF2 pathway activation attenuates ageing-related renal phenotypes due to alpha-klotho deficiency. theater plays nycWebKlotho ELISA Kits. ELISA Kits detecting Klotho can be used to research aging and bone loss or to study chronic renal failure (CRF). Klotho, also known as alpha-kl, is a full name of Klotho. Your search returned 416 Klotho ELISA Kit across 25 suppliers. theaterplein marketWebNational Center for Biotechnology Information the gold whisker ffxivWebNov 19, 2024 · The Klotho protein that was identified as the FGF23 co-receptor became known as αKlotho (encoded by the αKlotho gene; also known as KL ). βKlotho forms … theaterplein barneveldWebAlpha Klotho (α-Klotho) is a key player that integrates a multi-step regulatory system of calcium metabolism and phosphate homeostasis. Alpha Klotho (α-Klotho) was identified as an extremely down-regulated gene in the genetic mutation mouse (Klotho mouse) of which phenotype is very similar to various symptoms of human aging. the gold whisker