WebCaspase-8 (1C12) Mouse mAb 可检测全长 caspase-8 (57 kDa)、裂解中间介质 p43/p41 和 caspase-8 的活化片段 p18 的内源水平。 该抗体不会与其他 caspases 发生交叉反应。 物种反应性: 人 来源/纯化 使用与人类 … WebPolyclonal Antibody for studying Casp3. Cited in 4226 publications. Validated for WB, WB, IP, IHC. Highly specific and rigorously validated in …
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WebCaspase-3 (CPP-32, Apoptain, Yama, SCA-1) 是一个凋亡的关键执行者,因为它对许多关键的蛋白起着部分或全部的裂解作用,比如核酶多聚 (ADP-ribose) 聚合酶 (PARP) (1)。 caspase-3 的激活需要经过其未活化 … WebCaspase-1, or interleukin-1ß converting enzyme (ICE/ICEα), is a class I cysteine protease, which also includes caspases -4, -5, -11, and -12. Caspase-1 cleaves inflammatory cytokines such as pro-IL-1ß and …
WebApr 13, 2024 · P2rx1−/− mice showed a significant reduction in Caspase-3 activity (Fig. 2 d). At 6 h post-APAP (5 mM) stimulation, primary hepatocytes from both genotypes were stained with TUNEL to determine the degree of cell death. In response to the APAP challenge, the number of TUNEL-positive hepatocytes was significantly lower in … WebThe Caspase-3 Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, and Non-Human Primate antigen. The Caspase-3 Antibody has been …
WebCaspase-9 (C9) Antibody detects endogenous levels of the pro form of caspase-9 as well as cleaved fragments. Species Reactivity: Human, Mouse, Rat, Hamster, Monkey Source / Purification Monoclonal Antibody … WebCell Signaling Technology (CST): Antibodies, Reagents, Proteomics, Kits and Consumables 无载体蛋白抗体 - 让您的检测平台 准备就绪! 查看详情 经 Simple Western™ 验证的抗体 抗体偶联服务 探索阶段检测平台资源合集 定制组分 用 FastScan ELISA 试剂盒更快得到答案 通路 新产品 促销活动 CST博士云讲座 经销商查询 PhosphoSitePlus 技术支 …
WebThis was followed by incubation with primary antibodies against Ki67 (Abcam, Cambridge, MA, USA), Cleaved Caspase-3 (Cell Signaling Technology, Danvers, MA, USA), and PARD3 (Abcam) overnight at 4°C. After rinsing with PBS, cells were incubated with Alexa594-conjugated goat anti-rabbit IgG antibody.
WebApr 12, 2024 · The inflammasome is a multi-protein complex consisting of a sensor (NLRs), an adaptor (ASC), and an effector (caspase-1). A series of homotypic protein–protein interactions (NLRs PYD :ASC PYD and ASC CARD :caspase-1 CARD) enable inflammasome activation. phone in backpackWebApr 14, 2024 · Background: Studies have suggested the chemopreventive effects of anthocyanins on breast cancer carcinogenesis. This systematic review and meta-analysis aimed to evaluate the effect of anthocyanins on triple-negative breast cancer cells (TNBC) cultured in vitro. Methods: We searched for all relevant studies that evaluated the … phone in bagWebMoreover, the caspase inhibitor Z-VAD-FMK decreased the levels of cleaved caspase 3 in carvacrol-treated osteosarcoma cell lines (Figure 2 D) and partly rescued the antiproliferative effect of carvacrol treatment in these cell lines (Figure 2 E). The data indicate that carvacrol exposure can trigger apoptosis in osteosarcoma cell lines. phone in backpack clipartWebCaspase-9 (C9) Antibody 可检测内源性 Caspase-9 的前体形式和剪切片段。 物种反应性: 人, 小鼠, 大鼠, 仓鼠 , 猴 来源/纯化 使用重组人类 caspase-9 蛋白对动物进行免疫接种来产生单克隆抗体。 背景 胱天蛋白酶-9(ICE … how do you pair airpods to androidWebCleaved Caspase-8 (Asp374) (18C8) Rabbit mAb detects human Caspase-8 when cleaved at Asp374. This antibody will detect cleavage products containing the pro-domain with the p18 subunit as well as the p18 subunit alone. A band of unknown origin is detected at 25 kDa in some cell lines. Species Reactivity: Human Source / Purification phone in bag of riceWebThe primary antibody to LC3B (ab192890, Abcam, Cambridge, MA, UK) or Cleaved Caspase 3 (#9664, CST, MA, USA) was added dropwise to the sections and incubated overnight at 4 °C. Next day, slices were washed three times in PBS before incubation with secondary antibody (A0208, Bain-marie Biotech, Shanghai, China) for 1 h at room … how do you pair beats to iphoneWeb凋亡是一种严格受控的细胞自杀模式,以核固缩、细胞皱缩、细胞膜起泡和 DNA 片段化为特征。 Caspase 是半胱氨酸蛋白酶的一族,是细胞凋亡的中心调节分子。 启动子 caspase(包括 caspase-2、-8、-9、-10、-11 和 -12)与促凋亡信号紧密结合。 一旦激活后,这些 caspase 会剪切并激活下游效应器 caspases(包括 caspase-3、-6 和 -7),后 … phone in balloon trick